Our Researchers
Marco Leyton, PhD
Mental Illness and Addiction AxisResearch Focus
Research focus is the role of monoamines in mood and motivational states. The studies use a combination of monoamine depletion strategies and functional neuroimaging to investigate the role of catecholamines and serotonin in drug addiction, impulse-control and depression.
Keywords
Dopamine, serotonin, addiction, impulsivity, depression
Selected Publications
Leyton M, Dagher A, Boileau I, Casey K, Baker GB, Diksic M, Gunn R, Young SN, Benkelfat C. Decreasing amphetamine-induced dopamine release by acute phenylalanine/tyrosine depletion: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology 2004; 29:427-432.
Leyton M, Boileau I, Benkelfat C, Diksic M, Baker GB, Dagher A. Amphetamine-induced increases in extracellular dopamine, drug wanting, and novelty seeking: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology 2002; 27:1027-1035.
Leyton M, Okazawa H, Diksic M, Paris J, Rosa P, Mzengeza S, Young SN, Blier P, Benkelfat C. Brain regional -[11C]methyl-L-tryptophan trapping in impulsive subjects with borderline personality disorder. American Journal of Psychiatry 2001; 158:775-782.
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